Abstract: The objective of this work is to use a novel soft computing approach to predict the anti-inflammatory effect of bio copper nanoparticles. Using a modified technique, various doses of the Musa sapientum extract and copper nanoparticles were examined for their anti-inflammatory capabilities. Protein denaturation was evaluated, and an inhibition percentage was computed. The outcomes demonstrated that the quantity of copper nanoparticles raised the inhibition percentage, indicating a greater anti-inflammatory efficacy. In order to forecast the anti-inflammatory action based on the input variables of contact duration, operating temperature, and beginning concentration, an artificial neural network (ANN) was created. Using experimental data, the ANN model was developed, tested, and its performance assessed. The outcomes showed that the ANN model has a high degree of accuracy in predicting the anti-inflammatory action. In the context of summary, copper nanoparticles produced by Musa sapientum show considerable anti-inflammatory action. The ANN model and the suggested soft computing technique, which included the creation of copper nanoparticles, made an accurate prediction of the anti-inflammatory capabilities. This study aids in creating new methods for estimating the efficacy of bioactive nanoparticles in diverse therapeutic uses, such as the treatment of inflammation.

Dyuti Banerjee, G. Kiran Kumar, Farrukh Sobia, Subuhi Kashif Ansari, Anuradha. S and R. Manikandan, “Prediction of Anti-inflammatory Activity of Bio Copper Nanoparticle using an Innovative Soft Computing Methodology” International Journal of Advanced Computer Science and Applications(IJACSA), 14(6), 2023. http://dx.doi.org/10.14569/IJACSA.2023.0140681

@article{Banerjee2023,
title = {Prediction of Anti-inflammatory Activity of Bio Copper Nanoparticle using an Innovative Soft Computing Methodology},
journal = {International Journal of Advanced Computer Science and Applications},
doi = {10.14569/IJACSA.2023.0140681},
url = {http://dx.doi.org/10.14569/IJACSA.2023.0140681},
year = {2023},
publisher = {The Science and Information Organization},
volume = {14},
number = {6},
author = {Dyuti Banerjee and G. Kiran Kumar and Farrukh Sobia and Subuhi Kashif Ansari and Anuradha. S and R. Manikandan}
}